BASIC METABOLIC PANEL
The basic metabolic panel (BMP) is a set of seven to eight blood tests that
measure certain nutrients and electrolytes essential for basic body functions.
The basic metabolic panel typically measures the serum or plasma levels of
sodium, potassium, chloride, and bicarbonate in the body. The BMP is also used
to test other electrolytes such as: blood urea nitrogen (BUN), creatinine, and
glucose to check for or rule out diabetes or kidney disease.
In an emergency situation, the blood sample is processed right away, and the
results reported in less than an hour. Results of all hospital in-patient
routine tests are made available within three to six hours. Majority of
specimens handled at RML are for outpatient services and are usually shipped to
a central location. In such cases, reports are due back at the physician’s
office by the next day.
Sodium
Sodium is the major mineral in the blood and body fluids, and it plays a crucial
role in regulating the amount of water throughout the body. It passes in and out
of cells through pores called ion channels. This ionic transfer is essential for
many body functions, including the transmission of electrical signals in the
brain and muscles. Low sodium levels in children may be caused by severe
diarrhea or vomiting. Low sodium levels in the blood can result in swelling of
the brain as water moves into the brain cells. High sodium levels may be caused
by dehydration in which the amount of water lost is far greater than the amount
of sodium lost. High blood sodium levels can result in shrinking of the brain as
water moves out of the brain cells into the blood. Due to these changes, very
high or very low blood sodium results in confusion, weakness, lethargy, which
may lead to seizures.
Chloride
Chloride is an element in the blood and body fluid that functions like sodium to
maintain fluid balance. Disproportionate loss of chloride can lead to the body's
environment (Ph level) becoming more acidic.
Potassium
Potassium is the major electrolyte inside cells. Its passage in and out of cells
is essential to regulate heart contractions. High potassium levels can be
dangerous and may result in abnormal heart rhythms. Low potassium levels also
increase the risk of dangerous, abnormal heartbeat and are associated with
muscle weakness.
Bicarbonate
Bicarbonate is a measure of the alkalinity of the body's tissues. The
bicarbonate content of the body is delicately balanced by the kidneys and the
lungs. Its job is to prevent the body's environment from getting too acidic or
too basic.
Blood Urea Nitrogen (BUN)
Blood urea nitrogen (BUN) measures how well the kidneys are working. Urea is a
nitrogen-containing waste product created in the body through the metabolism and
breakdown of proteins. When the kidneys are not functioning properly, there is
an increase of BUN levels in the blood. Dehydration and excessive bleeding also
aid in elevating the BUN content of the blood. Malnutrition may also be
associated with low BUN levels.
Creatinine
Creatinine is a compound created by the breakdown of muscle protein. This
compound is then filtered and excreted through the kidney. Creatinine is
measured to determine kidney function. An increased level of creatinine in the
blood is an indication that the kidneys are not functioning properly. Kidney
failure may result from high creatinine levels. Both dehydration and muscle
damage from trauma can raise creatinine levels. Comparing BUN and creatinine
helps to locate the reason for kidney dysfunction.
Glucose
Glucose is the simple sugar produced by the body during digestion. Glucose is
the body’s main source of energy and is needed by cells for essential body
functions. The body produces two hormones, insulin and glucagon, which regulate
the amount of blood glucose in the body. The body stores unused glucose in the
liver as glycogen. Insulin increases the amount of glucose available to the
body's cells, and glucagon breaks down stored glycogen into glucose and releases
it into the blood stream.
Increase glucose levels in children is due to juvenile diabetes or the body’s
attempt to fight off severe infections. Hypoglycemia, or low blood glucose
levels, occurs if a child has liver damage or suffers from malnutrition.